Rosuvastatin Calcium (the active ingredient): This is a statin medication that lowers cholesterol levels.Inactive ingredients: These vary depending on the specific brand and formulation. Check your medication's label for a complete list. Common inactive ingredients might include cellulose, lactose, magnesium stearate, etc.
Primary hypercholesterolemia (high cholesterol): To lower LDL cholesterol ('bad' cholesterol), total cholesterol, and triglycerides.
Mixed dyslipidemia (abnormal lipid levels): To lower LDL cholesterol and triglycerides while raising HDL cholesterol ('good' cholesterol).
Homozygous familial hypercholesterolemia (a severe inherited form of high cholesterol): Used in conjunction with other cholesterol-lowering therapies.
Prevention of cardiovascular events: Reduces the risk of heart attack, stroke, and other cardiovascular events in patients with established cardiovascular disease or at high risk.
Advastat 20 Tab (Rosuvastatin) inhibits HMG-CoA reductase, a key enzyme in the production of cholesterol in the liver. By blocking this enzyme, rosuvastatin reduces the liver's ability to produce cholesterol, leading to a decrease in LDL cholesterol levels in the blood.
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children. Discard any medication that is outdated or no longer needed according to your pharmacist's instructions.
Dosage varies depending on individual needs and response to treatment. Your doctor will determine the appropriate dose for you.
It is typically taken orally once daily, with or without food.
Do not crush, chew, or break the tablets; swallow them whole.
Follow your doctor's instructions carefully and do not adjust the dosage without consulting them.
Muscle aches (myalgia) or pain (myopathy): This is a relatively common side effect, ranging from mild discomfort to severe muscle damage in rare cases.
Increased liver enzymes (detected via blood tests): Your doctor will monitor this.
Rare but serious side effects: Rhabdomyolysis (severe muscle breakdown), allergic reactions.
Headache
Nausea
Constipation
Diarrhea
Abdominal pain
Excessive alcohol consumption can increase the risk of liver damage, which is a potential side effect of rosuvastatin. Moderate alcohol consumption should be discussed with your doctor.
Rosuvastatin typically does not impair driving or operating machinery, but potential side effects like dizziness or fatigue should be considered.
Rosuvastatin is not recommended during pregnancy or breastfeeding. Discuss alternative treatments with your doctor.
Rosuvastatin is not typically used in children unless under strict medical supervision for specific conditions.
Kidney impairment can affect how rosuvastatin is processed. Dosage adjustments might be necessary.
Liver disease can increase the risk of liver damage from rosuvastatin. Your doctor will closely monitor your liver function.
Your doctor or pharmacist
The medication's package insert
Reputable medical websites (e.g., Mayo Clinic, NHS)
