Is the active ingredient.
Treatment of newly diagnosed glioblastoma multiforme (GBM) in adults.
Treatment of recurrent malignant glioma in adults after prior chemotherapy.
Temopine 20mg Capsule (Temozolomide) is an alkylating agent that acts by damaging DNA, preventing cancer cells from multiplying and ultimately leading to their death. It's a prodrug, meaning it's converted into its active form (methylating agent) inside the cells.
Store Temozolomide capsules at room temperature (20°C to 25°C) in a dry place. Protect from moisture. Keep out of the reach of children.
Dosage is determined by your physician based on your individual health and tumor type.
Typically taken orally once daily for a specific duration as prescribed.
Never alter the dosage or discontinue the medication without consulting your doctor.
Nausea and vomiting
Fatigue
Loss of appetite
Headache
Constipation
Myelosuppression (low blood cell counts)
Increased risk of infection
Allergic reactions (rare)
Alcohol may increase the risk of certain side effects, especially nausea and vomiting. Discuss alcohol consumption with your doctor.
Temozolomide can cause fatigue and dizziness, which may impair your ability to drive or operate machinery. Avoid these activities if you experience such side effects.
Temozolomide is potentially harmful to a developing fetus. Women who are pregnant or breastfeeding should not take this medication without consulting their doctor.
The safety and efficacy of temozolomide in children have not been fully established.
Kidney impairment can affect the way your body processes temozolomide. Your doctor may need to adjust your dosage or monitor your kidney function.
Liver problems can affect the way your body processes temozolomide. Your doctor may need to adjust your dosage or monitor your liver function.
Your oncologist or healthcare provider.
The prescribing information for Temozolomide provided by the manufacturer.
