Prescription Required.Why?
Is the active ingredient in most metformin formulations. different brands may contain inactive ingredients such as cellulose, povidone, and magnesium stearate which act as fillers or binding agents.
Type 2 diabetes mellitus: To improve blood sugar control.
Polycystic ovary syndrome (PCOS): To improve insulin sensitivity and regulate menstrual cycles (often used off-label).
Metgem 500mg Sr Tab (Metformin) reduces glucose production by the liver, improves insulin sensitivity in muscle and fat tissues, and decreases glucose absorption in the intestines. It does not stimulate insulin release like some other diabetes medications.
Store metformin tablets at room temperature, away from moisture and heat. Keep the medication in its original container.
Dosage is determined by your doctor based on your individual needs and response to treatment. It is usually started at a low dose and gradually increased.
Metformin is typically taken with meals to reduce gastrointestinal side effects.
Follow your doctor's instructions carefully. Do not change your dose without consulting your doctor.
Different formulations may have different administration instructions (e.g., immediate-release vs. extended-release).
Gastrointestinal issues (nausea, vomiting, diarrhea, abdominal pain)
Metallic taste in the mouth
Vitamin B12 deficiency (longterm use)
Lactic acidosis (rare but serious)
Avoid excessive alcohol consumption as it can increase the risk of lactic acidosis.
Metformin generally does not impair alertness, but potential side effects like dizziness should be considered.
Metformin is generally not recommended during pregnancy. Consult your doctor. Use during breastfeeding requires careful consideration and monitoring.
Metformin is not typically used in children, except in specific cases of type 2 diabetes.
Kidney function should be assessed before starting metformin, and the dose may need to be adjusted based on kidney function.
Liver function should be monitored during treatment, especially in patients with pre-existing liver conditions.
Your doctor or pharmacist
Medication package insert
Reputable medical websites (e.g., Mayo Clinic, NHS)
