Prescription Required.
Methotrexate is the active ingredient in this medication.It is available in various formulations, including tablets, injections, and oral solutions.
Rheumatoid arthritis
Psoriasis
Crohn's disease
Ulcerative colitis
Certain types of cancer
Ectopic pregnancy
Methotrexate works by slowing down the growth of cells, including those that cause inflammation and tissue damage. It does this by blocking the production of folic acid, which is essential for cell growth.
Store methotrexate at room temperature, away from light and moisture. Keep it out of reach of children and pets.
The dosage of methotrexate will vary depending on the condition being treated and the individual patient's needs.
It is typically taken once a week, either orally or by injection.
Your doctor will determine the correct dosage and frequency for you.
Nausea and vomiting
Diarrhea
Loss of appetite
Mouth sores
Hair loss
Liver damage
Bone marrow suppression
Increased risk of infections
Alcohol consumption can increase the risk of liver damage while taking methotrexate. It's important to limit alcohol intake or avoid it altogether.
Methotrexate can cause fatigue, dizziness, and drowsiness. Avoid driving or operating machinery until you know how this medication affects you.
Methotrexate is teratogenic, meaning it can cause severe birth defects. It should not be taken during pregnancy. It also passes into breast milk and can harm a breastfeeding infant. Do not breastfeed while taking methotrexate.
Methotrexate is not generally recommended for children unless under the care of a specialist.
Methotrexate can affect kidney function. Your doctor may monitor your kidney function while you are taking this medication.
Methotrexate can cause liver damage. Your doctor may monitor your liver function while you are taking this medication.
National Institutes of Health (NIH)
Food and Drug Administration (FDA)
American College of Rheumatology (ACR)
