Prescription Required.Why?
A thiazolidinedione (tzd) that improves insulin sensitivity.
A dipeptidyl peptidase-4 (dpp-4) inhibitor that enhances incretin hormone activity.
Type 2 diabetes mellitus in adults, particularly those inadequately controlled with metformin alone or who are intolerant to metformin.
Pioglitazone increases insulin sensitivity in peripheral tissues (muscle, liver, and adipose tissue), while vildagliptin increases levels of incretin hormones (GLP-1 and GIP) that stimulate insulin release and suppress glucagon secretion, leading to improved glycemic control.
Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
Dosage should be determined by a healthcare professional based on individual needs and response.
Typically administered once daily with or without food.
Heart failure (especially in patients with pre-existing heart conditions)
Fluid retention (edema)
Weight gain
Fractures (increased risk)
Upper respiratory tract infections
Headache
Nausea
Liver dysfunction (rare but serious)
Alcohol consumption should be limited or avoided as it can interfere with blood sugar control and increase the risk of liver damage.
May cause dizziness or fatigue; caution is advised.
Use is generally not recommended during pregnancy or breastfeeding. Consult a doctor.
Not indicated for use in children.
Dosage adjustment may be needed in patients with kidney impairment.
Regular monitoring of liver function is recommended, especially during initial treatment.
Please consult your doctor or pharmacist for detailed information and references to the specific drug formulation you are using.
