Pirfenidone

Is the active ingredient.

Treatment of mild to moderate idiopathic pulmonary fibrosis (IPF).

The exact mechanism of Pirfeza 400mg Tablet (Pirfenidone) in treating IPF is not fully understood, but it is believed to exert its effects through multiple pathways, including anti-fibrotic, anti-inflammatory, and antioxidant properties. It may reduce the production of transforming growth factor-beta (TGF-β), a key mediator of fibrosis.

Store at room temperature (20-25°C). Protect from moisture and light. Keep out of reach of children.

The recommended starting dose is typically 267 mg three times daily with food. The dose may be gradually increased to 801 mg three times daily as tolerated.

Dosage adjustments may be necessary based on individual patient response and tolerability. Always follow your doctor's prescribed dosage regimen.

Nausea

Diarrhea

Fatigue

Rash

Photosensitivity

Weight loss

Loss of appetite

Dizziness

Headache

Abdominal pain

Dyspepsia

Asthenia

Alcohol Consumption

Alcohol consumption may increase the risk of side effects. Consult your doctor.



While Driving or operating Machinery

Pirfenidone may cause dizziness or fatigue. Avoid driving or operating machinery if affected.



Pregnant & Breastfeeding Women

Not recommended during pregnancy or breastfeeding. Consult your doctor.



Children

Safety and efficacy in children have not been established.



Kidney

Dose adjustment may be necessary for patients with impaired kidney function.



Liver

Dose adjustment may be necessary for patients with impaired liver function. Liver function tests should be monitored regularly.

Your doctor or pharmacist

The official prescribing information for pirfenidone