Prescription Required.
Is the primary active ingredient.
Prevention of organ rejection in kidney transplant recipients.
Treatment of certain types of lymphangioleiomyomatosis (LAM).
Treatment of certain types of renal cell carcinoma (RCC) in combination with other therapies.
Siroboon 2 Tablet (Sirolimus) is an immunosuppressant that works by binding to the intracellular protein FKBP12. This complex then inhibits the mammalian target of rapamycin (mTOR), a kinase that plays a crucial role in cell growth, proliferation, and immune responses. By inhibiting mTOR, sirolimus suppresses the immune system, reducing the risk of organ rejection and potentially slowing tumor growth.
Store sirolimus at room temperature, away from direct sunlight and moisture. Keep out of reach of children. Discard any unused medication as instructed by your doctor or pharmacist.
Dosage is determined by your doctor and depends on your specific condition and response to treatment.
Sirolimus is typically administered orally, once daily.
Always follow your doctor's instructions carefully and do not change your dosage without consulting them.
Increased risk of infection.
Elevated cholesterol and triglycerides.
Headache.
Nausea and vomiting.
Diarrhea.
Mouth sores.
Skin rash.
Fluid retention.
High blood pressure.
Kidney problems.
Lung problems (rare).
Avoid excessive alcohol consumption as it may interact with sirolimus and increase the risk of side effects.
Sirolimus may cause drowsiness or dizziness. Avoid driving or operating machinery until you know how the medication affects you.
Sirolimus is not recommended during pregnancy or breastfeeding due to potential harm to the developing fetus or infant. Consult your doctor immediately if you become pregnant while taking sirolimus.
The use of sirolimus in children is limited and generally only used in specific circumstances under strict medical supervision.
Sirolimus can affect kidney function; regular monitoring of kidney function is necessary.
Sirolimus can affect liver function; regular monitoring of liver function is necessary.
Your doctor and pharmacist.
The prescribing information provided with the medication.
Reputable medical websites and journals (e.g., Mayo Clinic, National Institutes of Health).
