Somatostatin

Somatostatin is a naturally occurring hormone produced by the body. It is also available as a synthetic medication that mimics the effects of the natural hormone.Somatostatin formulations can include various forms, such as long-acting analogs like octreotide, lanreotide, and pasireotide.The specific ingredients in a somatostatin formulation may vary depending on the brand and type of medication.

Acromegaly (excess growth hormone production)

Neuroendocrine tumors (NETs) that secrete hormones like growth hormone, insulin, glucagon, or vasoactive intestinal peptide (VIP)

Control of bleeding from esophageal varices (swollen veins in the esophagus)

Treatment of diarrhea associated with carcinoid syndrome (a rare condition caused by tumors in the digestive system)

Treatment of severe diabetic gastroparesis (delayed gastric emptying in people with diabetes)

Offlabel use for other conditions, such as Cushing's disease and pancreatic cancer, may occur.

Somatin 3000 Inj (Somatostatin) works by inhibiting the release of various hormones, including growth hormone, insulin, glucagon, and others. This helps to regulate hormone levels and control symptoms associated with hormone-producing tumors and other conditions.

Somatostatin formulations should be stored as directed on the medication label. Generally, they are refrigerated and protected from light. Do not freeze the medication. Consult with your pharmacist for specific storage instructions.

Dosage and administration of somatostatin formulations vary depending on the specific condition being treated and the patient's individual needs.

Somatostatin analogs may be administered via subcutaneous injection, intravenous infusion, or oral administration. The frequency of administration and dosage will be determined by your healthcare provider.

It is important to follow the prescribed dosage and administration instructions carefully.

Nausea

Vomiting

Diarrhea

Abdominal pain

Headache

Weakness

Fatigue

Skin reactions at the injection site

Gallstones

Increased risk of infection

Hypoglycemia (low blood sugar)

Hyperglycemia (high blood sugar)

Fluid retention

Breathlessness

Heart failure

Liver problems

Alcohol Consumption

It is generally recommended to avoid alcohol consumption while taking somatostatin formulations, as it can worsen certain side effects.



While Driving or operating Machinery

Somatostatin formulations may cause drowsiness, dizziness, or impaired judgment. Avoid driving or operating machinery until you know how the medication affects you.



Pregnant & Breastfeeding Women

Somatostatin formulations may pose risks to pregnant and breastfeeding women. Discuss with your doctor the potential risks and benefits before taking this medication.



Children

Somatostatin formulations are not typically used in children, unless under specific medical guidance.



Kidney

Somatostatin formulations may be adjusted for patients with kidney problems. Consult your doctor for proper dosage and monitoring.



Liver

Somatostatin formulations may be adjusted for patients with liver problems. Consult your doctor for proper dosage and monitoring.

National Institutes of Health (NIH)

Food and Drug Administration (FDA)

The American Society of Clinical Oncology (ASCO)

The Endocrine Society

The National Organization for Rare Disorders (NORD)

Published medical journals and scientific articles on somatostatin formulations.